Download e-book for kindle: Advances in Food and Nutrition Research 51 by Steve Taylor

By Steve Taylor

ISBN-10: 0120164515

ISBN-13: 9780120164516

Advances in nutrients and nutrients learn acknowledges the vital dating among the meals and dietary sciences and brings jointly impressive and complete experiences that spotlight this dating. Contributions element the clinical advancements within the vast components of nutrition technological know-how and foodstuff are meant to make sure that nutrients scientists in academia and in addition to expert nutritionists and Read more...

summary: Advances in meals and meals study acknowledges the crucial courting among the meals and dietary sciences and brings jointly impressive and accomplished studies that spotlight this courting. Contributions element the medical advancements within the extensive parts of meals technology and food are meant to make sure that nutrition scientists in academia and in addition to specialist nutritionists and dieticians are stored expert pertaining to rising learn and advancements in those vital disciplines

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Enterolactone inhibited MDA-MB-435 cell adhesion at 1 mM concentration but not at 5 mM, whereas cell adhesion was not inhibited at 1 mM concentration of enterodiol. However, the 5 mM concentration of enterodiol was eVective against cell adhesion. In the MDA-MB-231 cells, enterolactone (5 mM) but not enterodiol inhibited cell adhesion. Tamoxifen prevented cell adhesion in both cell lines (Chen and Thompson, 2003). Combinations of enterolactone, enterodiol, and tamoxifen, at 1 mM concentration each, had the greatest reduction (36%) in cell adhesion.

Data to support this hypothesis was based on several observations. 4% (Prasad, 2005). Furthermore, the added lignan complex lowered the total cholesterol, LDL cholesterol, serum, and aortic malondialdehyde by 20%, 14%, 35%, and 58%, respectively. Unlike previous studies, the lignan enhanced HDL cholesterol by 25% and 30% in normocholesterolemic and hypercholesterolemic rabbits, respectively. Slightly higher (33% and 35%) reductions in total cholesterol and LDL cholesterol, respectively, were observed in rabbits on a 1% cholesterol diet containing 15 mg SDG/kg/day (Prasad, 1999).

A significant reduction in androstenedione-stimulated cell proliferation was also observed in enterolactone-treated MCF-7 cells. The enterodiol treatment did not reduce androstenedione-stimulated cell proliferation and in some instances (10 and 50 mM) increased cell proliferation (Brooks and Thompson, 2005). Saarinen et al. (2002) reported that enterolactone inhibited the growth of DMBA-inducted cancers in rats. 4 mM. Although weak, aromatase activity inhibition was observed. In a study by Chen and Thompson (2003), the eVects of enterolactone, enterodiol, tamoxifen, or combinations of these were evaluated in estrogen receptor negative human breast cancer cells MDA-MB-435 and MDA-MB231.

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Advances in Food and Nutrition Research 51 by Steve Taylor


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