Cytomel Side Effects: Common, Severe, Long Term

Thyroid hormones exert their physiologic actions through control of DNA transcription and protein synthesis. Triiodothyronine (T3) and L-thyroxine (T4) diffuse into the cell nucleus and bind to thyroid receptor proteins attached to DNA. This hormone nuclear receptor complex activates gene transcription and synthesis of messenger RNA and cytoplasmic proteins. This document does not contain all possible side effects and others may occur.

Recommended Dosage for TSH Suppression in Well-Differentiated Thyroid Cancer

Individuals who are hypothyroid have slower theophylline elimination. Therefore, when the concentration of thyroid hormone is returned to normal with liothyronine, the elimination of theophylline is increased. This reduces the concentration of theophylline in the body and can reduce the effectiveness of theophylline.

3 Recommended Dosage for TSH Suppression in Well-Differentiated Thyroid Cancer

Many people using this medication do not have serious side effects. If you are switching to Cytomel from any other thyroid medicine, stop using the other medicine before you start taking this medicine. Follow all directions on your prescription label and read all medication guides or instruction sheets. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Ask your healthcare professional how you should dispose of any medicine you do not use. This medicine is available only with your doctor’s prescription.

This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. Women who are post-menopausal or who use this medicine for a long time may have some bone loss, which could lead to osteoporosis. Talk with your doctor if you have questions or concerns about this. If https://christianomeloadvogado.com.br/pt-141-sci-peptides-effects/ you think you have become pregnant while using this medicine, tell your doctor right away.

• Consider changes in TBG concentration when interpreting T4 and T3 values.
• Therefore, when the concentration of thyroid hormone is returned to normal with liothyronine, the elimination of theophylline is increased.
• If you use medicine to treat high cholesterol (including cholestyramine, colesevelam, colestipol), Kayexalate®, or sevelamer, take liothyronine at least 4 hours before you take any of these medicines.
• Stop taking Cytomel and call your doctor if you have symptoms of thyroid toxicity, such as chest pain, fast or pounding heartbeats, feeling hot or nervous, or sweating more than usual.
• Approximately 80% of circulating T3 is derived from peripheral T4 by monodeiodination.

When switching a patient to CYTOMEL, discontinue levothyroxine therapy and initiate CYTOMEL at a low dosage. Gradually increase the CYTOMEL dose according to the patient’s response. Some side effects of liothyronine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.

The onset of activity of liothyronine sodium occurs within a few hours. The physiological actions of thyroid hormones are produced predominantly by T3, the majority of which (approximately 80%) is derived from T4 by deiodination in peripheral tissues. Animal studies have not been performed to evaluate the carcinogenic potential, mutagenic potential or effects on fertility of liothyronine sodium. Concurrent use of tyrosine-kinase inhibitors such as imatinib may cause hypothyroidism.

If it is near the time of the next dose, skip the missed dose. Do not double the dose to catch up unless your doctor instructs you to do so. Ask your doctor ahead of time what to do about a missed dose and follow your doctor’s specific directions. Current information shows that this drug may be used during pregnancy. Tell your doctor if you are pregnant because your doctor may need to change your dose. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).